Why You Need a Benchling Alternative: The Ultimate Comparison Guide

Benchling has multiple limitations. Given the needs of both life sciences and chemicals & materials industries, Benchling falls short on many crucial capabilities, including value from data, lab automation and the necessary breadth of tools and solutions.

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What Dotmatics offers

Microscope research


Digitizing and automating laboratory functions provides scientists rapid access to high-quality data so research can move seamlessly through lab departments more effectively.

AI & Machine Learning

AI & Machine Learning

Updating the architecture for automated capture of clean and trustworthy data enables powerful artificial intelligence and machine learning models.

DNA discovery

Multimodal Discovery

Leveraging a unified platform that supports testing different drug types across biology and chemistry helps cross-functional researchers solve a given problem.


Chemically-Modified Therapeutics

Access to a single source of truth provides chemists and biologists ways of capturing and viewing data that makes sense to them.


Dotmatics serves 10,000 customers and 2 million scientists worldwide. Its ELN solutions are purpose-built for life sciences, chemicals and materials, academic and government organizations of all sizes, including early-stage labs and global enterprises.

Other ELNs boast enterprise options, while growth has been primarily driven by a free version of the software with limited capabilities available to academic and student users.


Vastly superior chemistry features designed to capture experiments, molecules, samples, and assay data. With the Dotmatics ELN, you can also gather, analyze and improve visualization of project data to enable project teams to become more efficient and make informed decisions.

Other ELNs support registration of some small molecule entities via a third party system.


Dotmatics ELN is part of the larger group of Dotmatics products that are renowned as best-in-class solutions for biologics R&D, including GraphPad Prism, Geneious, and SnapGene, among others. Integrations with these products are co-developed for maximum interoperability.

Customers rely on third party software integrations, including Dotmatics products, to supplement their solutions.

Lab Automation

Automated processes for getting data in and out of the ELN to minimize human errors while meeting scale, security and automation standards.

Requires manual file and data processing by humans which is time intensive and not up to industry standards.

Assay Data Management

Meets current and future screening needs.

Cannot enable full experiment life cycle with the lack of assay data management.

Increase Insights from ELN Data with Dotmatics

Research data only has value when you can gain useful insights for analysis or when it’s clean and trustworthy to present for AI / machine learning models. With Dotmatics, search and accessibility is a primary consideration, not an afterthought, like other solutions.

Depth of Molecular Biology Capabilities

Dotmatics products include best-of-breed molecular biology applications such as Geneious Prime and SnapGene, as well as GraphPad Prism, the leading tool for scientific data analysis and visualization. Combining the power of these de facto end-user applications with comprehensive data centralization and search, the Dotmatics ELN provides a solution with unprecedented capabilities support.

Depth of Chemistry Capabilities

Dotmatics has a long history of high-performing chemistry capabilities. This is especially important with the rapid emergence of chemically-modified therapeutics, such as antibody-drug conjugates, stapled and bicyclic peptides, and various forms of RNA therapies. The ability of a single informatics platform that inherently supports both biology and chemistry is critical for this type of research.


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