Materials innovation typically combines a multitude of scientific disciplines, including synthetic chemistry, polymer science, formulation and process development. As a result, digitalizing materials innovation requires a data-centric platform approach that allows an inclusive view on all research data associated with any given project, rather than siloed systems where scientific disciplines deal with their data in separate IT environments.
Scientists need to make the most of their data to repurpose IP for new products and avoid duplication of fruitless efforts
Research managers need to increase lab throughput, avoid non-value-added work while monitoring projects for their chances of success
Organizations need free flow of information across customers, suppliers, partners and in-house teams while keeping IP safe and proprietary
Dotmatics implements the vast variability of R&D workflows that can be found in materials innovation with configurable templates. This means that all data types that belong to a specific experimental workflow are logically connected. This simplifies end user adoption because lab technicians only work on data fields that are relevant to them. It also solves data management issues since this approach eliminates challenges usually associated with siloed IT systems.
Using Dotmatics’ query framework scientists break down data silos by aggregating searches across in-house and external databases into single searchable project views. Structure-searching capability across multiple projects allows teams to re-apply corporate experience. Easy-to-use analytics tools included in Dotmatics’ data visualization tools allow project teams to analyze and visualize their data on a common platform for integrated decision-making ultimately giving faster product turn-around.
R&D data can only be correctly captured, stored, and analyzed if all relevant scientific domains capabilities are correctly represented within IT systems. Dotmatics electronic lab notebook (ELN) solutions implement a complete set of these domain-specific capabilities, including synthetic chemistry, formulations, analytical and process development.
Scientists plan and record experiments in Dotmatics ELN with templates configured to each experiment type. These can be highly structured, for example to capture the synthetic route of an active ingredient, or much more ad hoc performance-related experiments. Scientists are able to capture files such as spreadsheets, documents, images and videos to assemble a notebook page.
Dotmatics Browser is a powerful web-based search and reporting solution that provides federated searching across Dotmatics and third party research databases, enabling research scientists to access all of their data whenever they need it, irrespective of where it is stored.
Dotmatics Studies Notebook is an Electronic Laboratory Notebook (ELN) with flexible templating to capture, store and search experiments from all scientific disciplines.
Dotmatics Vortex is an interactive data visualization and analysis solution for scientific decision support. Building on and extending the spreadsheet paradigm, it provides the data manipulation, statistical analysis and sophisticated plotting capabilities required to explore and understand any complexity and size of data. Vortex is also scientifically aware providing native cheminformatics and bioinformatics analysis and visualizations.
The Dotmatics Platform is the common framework that supports the Dotmatics web-based scientific applications and allows them to work together to provide users seamless end-to-end workflows. The Platform supports managed deployments in the Cloud or self-supported deployments on premise. An open architecture enables workflows to include third-party software integration. When used together with Dotmatics Browser the Platform allows federated data access across corporate and external research data.The Dotmatics Platform is completely unified – it provides common data models, code and architecture to support business workflows that span the capabilities of the individual applications. This is important for enterprise enablement of research organizations, providing ease of maintenance and development. It gives the lowest possible total cost of ownership compared to platforms that support their applications with less tightly integrated collections of multiple technologies and/or architectures with multiple development histories.
Dotmatics Chemselector manages very large chemistry datasets with fast search and trivially simple maintenance/update. It has a modern user interface focused on browsing and filtering for molecule, reagent and sample selection. The available eMolecules+ for Chemselector dataset provides access to highly curated eMolecules sourcing data.
eMolecules+ for Chemselector
Dotmatics Cascade manages the requesting and assignment of laboratory tasks, and tracking the progression of samples, across multiple teams within an organization or across a collaborating network.
Dotmatics Reaction Workflows is a graphical environment that enables scientists to build and execute data processing workflows to perform common cheminformatics tasks, such as library enumeration, structure normalization and compound profiling. Users build workflows in a drag-and-drop environment by selecting and connecting nodes that provide inputs (e.g a list of reagents) and outputs (e.g. view in Dotmatics Vortex) or perform actions (e.g. perform a reaction), configuring them with data and then executing the workflow to produce results. Many different tasks can be configured including:
Dotmatics Inventory is a fully searchable sample and materials inventory that tracks chemicals, biologics, instruments and associated data across a hierarchy of locations and manages the dispensing and plating workflows, as samples are moved through an R&D process.
Dotmatics Pinpoint is a chemical cartridge for indexing and searching chemistry within Oracle databases.
Pinpoint enables indexing of chemical structures, calculations of physical chemical properties and substructure searches within an Oracle database. It is used to support structure searching with Dotmatics Browser, check for structural uniqueness and register molecules in Dotmatics Register, and store and search chemical reactions in Dotmatics Studies Notebook.
Dotmatics Elemental is a chemical sketcher that enable scientists to draw, edit and save structures and reactions, and calculate properties.
Dotmatics Register is a web-based compound and batch registration system used to maintain corporate chemical registration and reagent databases.