Product – Studies

Defines analysis protocols for plate and non-plate based assays
Provides out-of-the-box and custom assay protocols, curve fit calculations, plate readers, and plate layouts captured and stored for re-use
Supports very high data volume assays
Defines business rules for very automated classification of results
Manual or automated processing allows screening scientists to apply the screening protocols to process raw instrument and validate the results, or experiment creation and processing to be driven via an automation layer.
Once completed and validated, screening results are immediately available via Browser to the project team

Flexible – Designed for all types of study management
Scalable – Designed to handle today’s high data volume assays with automation and business rules making the processing huge result sets feasible
Visual – high performance information-rich visualizations to efficiently analyze and/or review assay experiments
Screening – plate and non-plate-based assays
- %inh, IC/EC50, KI, user-defined analysis
- In-vivo studies using document templates
- Kinetic studies
- Complex assays such as ELISA, MIC, HCS
Integrated
- Obtains samples and plates directly from Inventory
- Pushes data directly to Dotmatics Vortex for advanced analytics
- Publishes results directly to Dotmatics Browser for search and reporting
- Creates assay experiments in Dotmatics Studies directly from Dotmatics Cascade requests
- Shares a common framework with Dotmatics Studies Notebook to manage workflow
- Links to Dotmatics Gateway, Register and Bioregister
Accessible – Web-based for easy deployment with no client install. Hosted on-premise or in the cloud
Collaborative – Cloud-hosted deployments support external collaborations, such as assay execution by CROs

Supports a wide variety of assay types including HTS, HCS, dose-response, DMPK
Out-of-the-box set of assay templates, plate readers, plate layouts and calculation
Flexible protocol definitions
Captures custom definitions of plate readers, plate layouts and calculations for re-use in protocols
Captures all data related to an experiment, whether structured or unstructured
Structured workflow to analyze raw assay data including validation and optional QA before publication of results
Manually define experiments, load and analyze results or drive experiment creation/analysis and result classification via RESTFul APIs from an automation layer
RESTFul APIs allow the integration of assay data management with third party systems such as Inventory systems to obtain screening samples and plates
Supports in-house and outsourced assays and cross company validation workflows
Fully integrated in the Dotmatics suite
Assay results published to Dotmatics Browser so they can immediately be searched in association with corporate registry and other data sources

Studies