ドットマティクスの統合ソリューションは、ヒットやリードの同定からリードの最適化、候補の選定までの低分子創薬のワークフローをサポートします。実験装置からのデータ、実験、分子、サンプル、アッセイデータを記録し、実験室のワークフローを効率化。意思決定支援ツールでは、プロジェクトデータの収集、可視化、分析ができ、プロジェクトチームは十分な情報に基づいた迅速な意思決定を行うことができます。
低分子創薬プロジェクトは、部門、科学分野、物理的な場所、時には会社を横断します。プロジェクトを効率的に遂行するためには、リクエスト、データ、結果がすべてのメンバー間でシームレスに流れる必要があります。
プロジェクトチームのすべてのメンバーは、保存場所に関係なく、許可を得たすべてのプロジェクトデータにリアルタイムでアクセスし、プロジェクトの進行に関する最適な意思決定を行う必要があります。
実験装置からのデータ収集・分析を自動化し、部門横断的な各ワークフローをシームレスに接続する必要があります。
ドットマティクスのソリューションは、共同研究ネットワーク全体でのコラボレーションに最適です。実験や研究データはリアルタイムで共有でき、イベントフィードやダッシュボードには最新のステータスが表示されます。また、コラボレーションツールやコミュニケーションツールを使って共同研究を効率化することができます。
Find out more about how you can use Dotmatics to improve your collaboration:
ドットマティクスのソリューションは、実験装置からデータを自動で収集し、データレイクに安全に保存することができます。また、収集したデータを解析してデータやメタデータを抽出し、検証を行うことができます。結果は電子実験ノートやアッセイデータ管理システムに直接送信することができます。ヒューマンエラーを排除した、リアルタイムでクリーンなデータはAI/MLで使用でき、科学者の意思決定に役立てることができます。
Dotmatics Vortex is an interactive data visualization and analysis solution for scientific decision support. Building on and extending the spreadsheet paradigm, it provides the data manipulation, statistical analysis and sophisticated plotting capabilities required to explore and understand any complexity and size of data. Vortex is also scientifically aware providing native cheminformatics and bioinformatics analysis and visualizations.
The Dotmatics Platform is the common framework that supports the Dotmatics web-based scientific applications and allows them to work together to provide users seamless end-to-end workflows. The Platform supports managed deployments in the Cloud or self-supported deployments on premise. An open architecture enables workflows to include third-party software integration. When used together with Dotmatics Browser the Platform allows federated data access across corporate and external research data.The Dotmatics Platform is completely unified – it provides common data models, code and architecture to support business workflows that span the capabilities of the individual applications. This is important for enterprise enablement of research organizations, providing ease of maintenance and development. It gives the lowest possible total cost of ownership compared to platforms that support their applications with less tightly integrated collections of multiple technologies and/or architectures with multiple development histories.
Blueprint is a web-based visualization and scientific analytics application. It is designed to help project scientists working on small molecule discovery projects to visualize and analyze their data, and to help them to design their next set of compounds to make.
Dotmatics Chemselector manages very large chemistry datasets with fast search and trivially simple maintenance/update. It has a modern user interface focused on browsing and filtering for molecule, reagent and sample selection. The available eMolecules+ for Chemselector dataset provides access to highly curated eMolecules sourcing data.
Chemselector
eMolecules+ for Chemselector
Dotmatics Cascade manages the requesting and assignment of laboratory tasks, and tracking the progression of samples, across multiple teams within an organization or across a collaborating network.
Dotmatics Studies is a highly flexible, innovative screening data management solution to capture and analyze all types of screening experiments from high content (HCS) and high throughput (HTS) to dose-response and DMPK studies.
Dotmatics Reaction Workflows is a graphical environment that enables scientists to build and execute data processing workflows to perform common cheminformatics tasks, such as library enumeration, structure normalization and compound profiling. Users build workflows in a drag-and-drop environment by selecting and connecting nodes that provide inputs (e.g a list of reagents) and outputs (e.g. view in Dotmatics Vortex) or perform actions (e.g. perform a reaction), configuring them with data and then executing the workflow to produce results. Many different tasks can be configured including:
Dotmatics Inventory is a fully searchable sample and materials inventory that tracks chemicals, biologics, instruments and associated data across a hierarchy of locations and manages the dispensing and plating workflows, as samples are moved through an R&D process.
Dotmatics Pinpoint is a chemical cartridge for indexing and searching chemistry within Oracle databases.
Pinpoint enables indexing of chemical structures, calculations of physical chemical properties and substructure searches within an Oracle database. It is used to support structure searching with Dotmatics Browser, check for structural uniqueness and register molecules in Dotmatics Register, and store and search chemical reactions in Dotmatics Studies Notebook.
Dotmatics Elemental is a chemical sketcher that enable scientists to draw, edit and save structures and reactions, and calculate properties.
Dotmatics Register is a web-based compound and batch registration system used to maintain corporate chemical registration and reagent databases.