Speakers - Symposia 2018

Dotmatics Symposium Melbourne, Australia

Inhee Choi, RPh, PhD

Senior Researcher, Bioinformatics Group

Institut Pasteur Korea (IPK)

Inhee Choi is highly experienced in computational aided drug design with a pharmacist background. She has a PhD in computational aided drug design from College of Pharmacy, Ewha Womans University in Korea and completed her postdoctoral training at the National Institute of Health (NIH), Maryland, USA. Inhee joined Institut Pasteur Korea (IPK) in 2010 upon returning to Korea. She continues to be actively involved in various bio-cheminformatics research projects. She manages and organises chemical and biological data information within her groups in the graduate school, NIH, and IPK.
 

Bradley Doak, PhD

Postdoctoral Research Scientist

Monash University

Brad completed a PhD in Synthetic Medicinal Chemistry at MIPS under the supervision of Martin Scanlon and Jamie Simpson in the area of fragment-based drug design. He then undertook postdoctoral training with Jan Kihlberg at Uppsala University, Sweden, looking at drug discovery beyond the rule of 5 with particular attention on macrocycles. Brad then returned to Monash University with the formation of the Monash Fragment Platform to continue working on fragment-based drug design, particularly early hit to lead development. Brad’s interests include medicinal chemistry and chemoinformatics in fragment development, particularly in the development of libraries. Brad’s talk will focus on the work currently undertaken on the development and design of libraries for early stages of development in fragment-based drug design, focusing on the use of designed generic reagent libraries for development when little to no structural information is available.
 

Wolfgang Jarolimek

Head of Drug Discovery

Pharmaxis

Wolfgang joined Pharmaxis in September 2010 as Manager in vitro Pharmacology and was appointed Head Drug Discovery in August 2012.
He has more than 15 years’ experience in pharmaceutical drug discovery and has published more than 30 peer reviewed articles. From 2002 to 2010 Wolfgang was Director of Assay Development and Compound Profiling at the GlaxoSmithKline Center of Excellence in Drug Discovery in Verona, Italy. In addition to chairing early drug discovery efforts locally he also had global responsibilities for ion channel screening and implementing safety-related screening. From 1998 to 2002 he worked at the Neuroscience Center of Merck, Sharp and Dohme in Harlow, England, as Senior Research Scientist in the electrophysiology group. Wolfgang previously spent 8 years as post-doc at the Max-Plank Institute in Munich, Germany; Baylor College of Medicine, Houston, Texas; Rammelkamp Center, Cleveland Ohio; and University of Heidelberg, Germany.
Wolfgang holds a BSc in Pharmacy and a PhD from the University of Saarbrücken, Germany. In 1997 he became Assistant Professor in Physiology at the University of Heidelberg, Germany.
 

Guilhem Morra

Science Systems Analyst

Plant and Food Research

I have a background in heterogeneous catalysis and high throughput screening. I hold an MSc from École Centrale de Lyon and a PhD in Chemistry from Université Claude Bernard in France. I have worked for 8 years with Johnson Matthey (UK) where I was helping our Teesside research centre with scientific data management. I have started with Plant & Food Research, New Zealand biggest Crown Research Institute in November 2016 to manage the implementation of Dotmatics across the institute.
 

Rebecca Moss

Manager, Research Technologies

Cancer Therapeutics CRC (Ctx)

Rebecca has a background in high throughput screening and data management. She holds a BSc in Applied Biology/Biotechnology (Hons) from RMIT University Melbourne. Rebecca has worked at the WEHI for 16 years and has been involved with Cancer Therapeutics (CTx) since 2008 when an electronic laboratory notebook was first introduced.

Rebecca is responsible for developing and maintaining the CTx eResearch platform, which includes the infrastructure, data systems and the applications. The eResearch Platform hosts applications such as Atlassian, SharePoint and Dotmatics. These tools facilitate the analysis and reporting of research data generated at all stages of the drug discovery pipeline.

Rebecca’s talk will focus on CTx's journey to Dotmatics and will highlight current workflows and customised features that have become essential to the data management of their successful drug discovery program.
 

Grant Stuchbury

Senior Biologist

Qeddi

With a background in neurobiology and oncology, I have been involved in small molecule drug discovery for the past 8 years. My first post-doctoral position was at Griffith University, as part of the Cancer Therapeutics CRC (CTx), where I developed and performed high throughput screening campaigns, with a focus on high content imaging. In my current role as Senior Biologist at QEDDI, I established the biology laboratory and now lead the team in designing, developing and validating robust, reliable and relevant biological assays for both high throughput screening and ongoing small molecule development.
 

Inhee Choi, RPh, PhD

Senior Researcher, Bioinformatics Group

Institut Pasteur Korea (IPK)

Inhee Choi is highly experienced in computational aided drug design with a pharmacist background. She has a PhD in computational aided drug design from College of Pharmacy, Ewha Womans University in Korea and completed her postdoctoral training at the National Institute of Health (NIH), Maryland, USA. Inhee joined Institut Pasteur Korea (IPK) in 2010 upon returning to Korea. She continues to be actively involved in various bio-cheminformatics research projects. She manages and organises chemical and biological data information within her groups in the graduate school, NIH, and IPK.
 

Dotmatics Symposium Cambridge, UK

Tatiana Guzzo

Head Of Chemistry Lab

C4T

Dr Tatiana Guzzo has a Master’s Degree in Industrial Chemistry (110/110), attained at the University of Rome “Sapienza”. At C4T since 2006, she is a senior research scientist with proven expertise in Organic Synthesis and Medicinal Chemistry. She is project Leader of C4T research services to major pharma companies and of key Med Chem Proprietary Projects (e.g., FP7 – Florinash; MIUR – IVASCOMAR). She is co-inventor of a new class of CB2 modulators (C4T Patent). She is in charge of the scientific management of the different research teams. She has been tutor of 6 stages of Organic Synthesis training. She also contributed to the implementation of C4T Platform for Advanced NMR studies for industrial application (i.e., DOSY-NMR; isotope NMR; 2D-NMR). She gave relevant contribution to the implementation of C4T Quality & Safety Management System (ISO 9001 and OHSAS 18001). As “Cultore della materia”, she is teaching assistant for the course in Combinatorial Chemistry and Drug Design at the Chemistry Department of the University of Rome “Tor Vergata”. Since 2015 in charge of the Training Module in <Principles of drug discovery> for the II Level Master: “Sviluppo preclinico e clinico del farmaco: aspetti tecnico-scientifici, regolatori ed etici” at Università Cattolica del Sacro Cuore – Rome.
 

Bernard Lesch

International Research Project Lead

Grünenthal Innovation

Leading multidisciplinary teams to achieve the goals is Bernard's passion. With more than ten years experience in the pharmaceutical industry, Bernhard offers a strong background in synthetic organic chemistry, project managament and medicinal chemistry. Besides process development and lead finding/optimzation projects in medicinal chemistry, he has participated in and managed IT infrastructure projects, demonstrating leadership even in unfamiliar areas.
 

Christina Majer

Head of Screening and Data Systems

Ribon Therapautics

Christina Majer is Head of Screening and Data Systems at Ribon Therapeutics where she oversees the compound management team, their database, and the primary screening of all library compounds in two different assay platforms. Her experience includes building integrated workflows from the ground up, including compound management, assay development and screening, data management, and outsourcing across multiple sites. Prior to Ribon, Christina was at Warp Drive Bio, Epizyme, Inc, and Millennium (Takeda).
 

Gary Nugent

Senior Scientific Officer

The Institute of Cancer Research

After studying Chemistry with Pharmaceutical and Forensic Sciences at the University of Bradford, Gary joined Evotec as a synthetic chemist. He then moved to Summit Plc as a medicinal chemist before swapping roles and moving into informatics data management . In 2009 he joined the CRUK Cancer Therapeutics Unit at the Institute of Cancer Research, London where he manages the Dotmatics informatics platform. Working with the multidisciplinary project teams, he is responsible for customising Dotmatics to ensure that data is easily accessed and displayed in an appropriate format.
 

Aravind Prasad

Scientist 1, Computational Chemistry

Celgene

Aravind Prasad is a Bioinformatics Scientist at Celgene in the Computational Chemistry group. He has previously worked in various capacities at major biotechnology companies as well as startups in the US and India.

At Celgene, Aravind supports New Target drug discovery efforts and is deeply involved in efforts to bring in silico technology solutions to drug discovery scientists. While he was at Avila Therapeutics, he developed the Avilomics™ covalent drug discovery platform that has successfully generated over a dozen development candidates so far. Prior to this he coordinated with a team of developers to build an Integrated Cheminformatics Expert System across global sites for a large pharma client. Aravind holds a Masters degree in Bioinformatics from Northeastern University and a bachelors degree in Electronic and Communications Engineering from Osmania University in India.
 

Jean Richardson

IT Scientist

Debiopharm International SA

Jean is an experienced Life Sciences Application Scientist analyzing business needs and implementing informatics solutions for the Research and Discovery sectors. Currently working at Debiopharm International S.A. Previously worked at Dotmatics and 15 years at Merck Serono. Trained as a physicist with a Doctor of Philosophy (Ph.D.) focused in High Energy Physics at CERN from the University of Liverpool.
 

René Van Den Bersselaar

Director, Information Technology

Debiopharm Group

Rene Van Den Bersselaar completed his degree in Biochemistry and Molecular Biology at Utrecht University, which he followed with a number of high profile IT positions at Merck Sharp and Dohme and Vivenics, before joining Debiopharm International in 2017. He is an IT entrepreneur with over 25 years of experience in the Pharmaceutical industry including R&D, Manufacturing, Engineering, Marketing & Operations and Patents. Rene enjoys shaping strategic business directions and translating these into high-level program requirements, leveraging best practice and introducing new cost effective methods and approaches to people and project portfolio management.
 

Dotmatics Symposium Boston, USA

Michael Beluch

Lead, Digital Capability Management, Leads Discovery and Optimization

Bristol-Myers Squibb

Mike Beluch is the Lead Digital Capability Manager for the Leads Discovery & Optimization group at Bristol-Myers Squibb. Mike has worked in the chemical and pharmaceutical industries for 25 years, starting his career at the bench as a Molecular Biologist, specializing for many years in nuclear hormone receptors and cholesterol efflux pathways. In 2004, Mike transitioned to IT at BMS, advancing a 'user-perspective', while working to develop, integrate, and support applications used in Research and Discovery Biology. His responsibilities have been to support existing and emerging technologies in the High-throughput screening group via software development and third-party software integration. In 2019, Mike transitioned to a broader role as a DCM Lead for LDO, responsible for defining strategic technology road-maps and developing solution architectures for new business capabilities.
 

Christina Majer

Head of Screening and Data Systems

Ribon Therapautics

Christina Majer is Head of Screening and Data Systems at Ribon Therapeutics where she oversees the compound management team, their database, and the primary screening of all library compounds in two different assay platforms. Her experience includes building integrated workflows from the ground up, including compound management, assay development and screening, data management, and outsourcing across multiple sites. Prior to Ribon, Christina was at Warp Drive Bio, Epizyme, Inc, and Millennium (Takeda).
 

Daniel McMasters

Director, Modeling & Informatics

Vertex Pharmaceuticals

Daniel McMasters is a Director in the Modeling & Informatics group at Vertex Pharmaceuticals based in Boston. His group is responsible for advancing the drug discovery projects at Vertex’s Boston research site with computational chemistry and cheminformatics. He also contributes to strategic and company-wide efforts in data visualization, predictive modeling, and in silico ADME and toxicity. Prior to Vertex, he worked from 2000 to 2016 for Merck & Co. He obtained a B.S. in chemistry from Stanford University, M.Sc. in organic chemistry from the University of Chicago, and D.Phil. in physical chemistry from the University of Basel, and did postdoctoral work at the Biographics Laboratory in Basel.
 

Dotmatics Symposium San Francisco, USA

Donogh O'Mahony

Staff Scientist

Nektar Therapeutics

Donogh O'Mahony joined Nektar Therapeutics in 2011, where he is a Staff Scientist; currently he divides his time between new chemical entity design and synthesis, and leading the implementation effort of the Dotmatics suite within discovery research. Prior to this he worked on anti-infectives at NovaBay Pharmaceuticals, and CNS indications at Renovis (acquired by Evotec). He received his fist introduction to the power of cheminformatics solutions in 1999 upon joining SIDDCO (acquired by Discovery Partners Int’l, Inc.) where he worked in chemical library synthesis. Donogh completed BSc and PhD degrees at Imperial College London, and conducted further postdoctoral research at Montana State University Bozeman.
 

Katherine Walker

Research Associate II - Chemistry

DiCE Molecules

Katherine studied chemistry at Wesleyan University in Middletown, Connecticut and has been working at DiCE Molecules since she graduated. In her role at DiCE, she is focused on chemistry development for DNA encoded libraries. She has also been heavily involved in the implementation of Dotmatics and testing of custom Dotmatics solutions at DiCE.
 

Dotmatics Symposium Tokyo, Japan

Tanja Gellert

Chemical Technical Assistant

Morphosys AG

Tanja Gellert graduated is a Chemical Technical Assistant at Chemieschule Elhardt, Munich. Tanja has worked at different Universities firstly in the field of Genetics and later in Immunology. In 2006 she joined MorphoSys, working as a Technical Assistant in the Discovery and Alliances Unit on customer & MorphoSys own projects. Since the implementation of the integrated R&D database at MorphoSys she is also a critical contributor of the support & development team and working together with IT as a “connector” between the Lab and IT department.
 

Takayuki Kochi

Manager, Research Platform

Asahi Kasei Pharma Corporation

2000 : Department of Material and Life Science, Graduate School of Engineering, Osaka University
2000 : Hitachi Software Engineering Co., Ltd.
2013 : AsahiKasei Pharma Corporation
2018 : Manager, Research Platform, Laboratory for Medicinal Chemistry
 

Hiroshi Uchida

Manager, Synthetic Research Department

ASKA Pharmaceutical Co., Ltd.

1997:School of Pharmaceutical Sciences, University of Shizuoka, Ph.D.
1997:Teikoku Hormone MFG. Co., Ltd., Researcher, Medicinal Chemist
2005:ASKA Pharmaceutical Co., Ltd., Researcher, Medicinal Chemist
2008:ASKA Pharmaceutical Co., Ltd., Manager, Synthetic Research Department
 

Dotmatics Symposium Osaka, Japan

Tanja Gellert

Chemical Technical Assistant

Morphosys AG

Tanja Gellert graduated is a Chemical Technical Assistant at Chemieschule Elhardt, Munich. Tanja has worked at different Universities firstly in the field of Genetics and later in Immunology. In 2006 she joined MorphoSys, working as a Technical Assistant in the Discovery and Alliances Unit on customer & MorphoSys own projects. Since the implementation of the integrated R&D database at MorphoSys she is also a critical contributor of the support & development team and working together with IT as a “connector” between the Lab and IT department.
 

Takayuki Kochi

Manager, Research Platform

Asahi Kasei Pharma Corporation

2000 : Department of Material and Life Science, Graduate School of Engineering, Osaka University
2000 : Hitachi Software Engineering Co., Ltd.
2013 : AsahiKasei Pharma Corporation
2018 : Manager, Research Platform, Laboratory for Medicinal Chemistry
 

Hiroshi Uchida

Manager, Synthetic Research Department

ASKA Pharmaceutical Co., Ltd.

1997:School of Pharmaceutical Sciences, University of Shizuoka, Ph.D.
1997:Teikoku Hormone MFG. Co., Ltd., Researcher, Medicinal Chemist
2005:ASKA Pharmaceutical Co., Ltd., Researcher, Medicinal Chemist
2008:ASKA Pharmaceutical Co., Ltd., Manager, Synthetic Research Department
 

Dotmatics Symposium Seoul, Korea

Tanja Gellert

Chemical Technical Assistant

Morphosys AG

Tanja Gellert graduated is a Chemical Technical Assistant at Chemieschule Elhardt, Munich. Tanja has worked at different Universities firstly in the field of Genetics and later in Immunology. In 2006 she joined MorphoSys, working as a Technical Assistant in the Discovery and Alliances Unit on customer & MorphoSys own projects. Since the implementation of the integrated R&D database at MorphoSys she is also a critical contributor of the support & development team and working together with IT as a “connector” between the Lab and IT department.
 

Mr. Jae Sung Hwang

Research Scientist

Dong-A ST

Jaesung Hwang studied a computation chemistry for his masters degree in Soongsil University, Seoul, Korea. He started his career at JW JoongWae research center in 2003 in field of molecular modeling and computer-aided drug discovery (CADD) and he joined current Dong-A ST research center in 2010 as senior research scientist in discovery technology research lab. Currently, he has been focusing on more potent & selective inhibitor design with published x-ray and docking ADME/T prediction as computer-aided drug design (CADD) roles and is responsible for in-house library database system management of same research center
 

Hanjo KIM, PhD

Principal Researcher

CJ Healthcare, New Drug Research Center

After Hanjo received his PhD (2004 at Yonsei University) in organic chemistry, he worked in the field of molecular modeling and cheminformatics. His previous positions include team leader at BMDRC, research staff at NUS, and head of R&D center at Equisnzaroo inc. In late 2015, he joined CJ Healthcare as a Principal Researcher, New Drug Research Center.
Currently, Hanjo’s main interest lies in support/education/deployment of molecular modeling and cheminformatics techniques for medicinal chemists. He is also developing and maintaining in-house software/scripts for specific tasks of pharmaceutical R&D process.
 

Soolki Kwon

Senior Scientist

Yuhan

1998~2005 Kyunghee University College of Life Science, Genetic engineering, BS
2006~2008 Yonsei University Graduate School of Medicine, Cell biology & Pharmacology, MS
2008~2010 Yonsei University, Department of Biochemistry & Molecular Biology, Research Scientist
2010~2016 CrystalGenomics R&D Institute, Discovery Biology, Senior Research Scientist
2016~ Yuhan R&D Institute, Chemistry&Chemical Biology, Senior Scientist
 

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